Generic semaglutide could reshape diabetes drug coverage in Canada

People vaccinated against HPV have lower risk of head and neck cancer, study suggests

A single-dose amber codon carrying live attenuated vaccine elicits pan-sarbecovirus immunity and blocks SARS-CoV-2 transmission

In a trial of 393 patients in the United States, the highest dose cut eczema skin symptoms by 61%, against 31% on a placebo, after 16 weeks.

Over 25% of patients have body shapes that don't fit standard, universal templates for placing robotic surgical tools

14 week, Phase 4, Open Label, Decentralized Study finds that Viloxazine ER reduced ADHD symptoms by 45.3% in adults with comorbid depression/anxiety

More leucovorin prescribed to kids after federal officials touted its unproven benefits for autism

Adverse Events Associated with Incretin-Based Therapies: A Narrative Review on Mechanisms, Clinical Management, and Risk Mitiga

Study finds less invasive heart bypass surgery as good as traditional methods, and patients recovered faster after minimally invasive procedure

Naturalistic observational study finds Atomoxetine and Methylphenidate significantly improved self-esteem and quality of life in adults with ADHD

Urinary stones share universal molecular signatures across humans and animals

Symptom-level transcriptome-wide associations of NMN-nominated KEGG pathways in major depression: a distributed endocytosis–hypersomnia signal, gene-weighted immune and motor cassettes…

Cross-Ancestry TWAS Suggests Conserved Ageing–Immune Signatures and a Putative NAD/Sirtuin Axis in Schizophrenia

A rare childhood leukemia (ETV6::RUNX1-like) behaves aggressively, carries a high relapse risk, and surprisingly affects 12% of Down syndrome patients

Experimental treatment kills prostate tumor cells while reawakening antitumor immunity

Berkeley Lab researchers make breakthrough in treatment of incurable Huntington’s disease

Acupuncture Seems to Rewire The Brain in Depression, Scans Reveal

Comparative TWAS suggests predominantly shared ageing-related gene expression patterns with quantitative differences in treatment-resistant schizophrenia

Glial-adjusted residual transcriptomics with leave-one-out transcriptome-wide association study influence analysis prioritizes GALNT6 and other high-impact genes in Alzheimer’s disease

A phone-based adherence app raised tuberculosis treatment success from 74% to 82% and cut dropout by nearly a third in Argentina.

New study on heart failure finds Urolithin A, a compound some people's gut bacteria produce from pomegranates, improved heart relaxation and reduced fibrosis in mice with the stiff-heart form of heart failure

Lymphatic vessels invade bone in disease but are absent in health and regeneration

Protracted exposure to low-dose ionising radiation and cancer incidence among Canadian nuclear power plant workers: Canadian NPPWs have increased risks of prostate cancer and melanoma from low-dose ionising radiation exposure

Doctors Found 4 Autoimmune Diseases in One Woman at One Time: 40-year-old woman in China was already diagnosed with 3 - ulcerative colitis, autoimmune hepatitis and primary sclerosing cholangitis

In a trial of 20 patients in China, those injected with lab grown heart muscle cells walked further and had better blood flow than bypass surgery alone

A Prospective, Randomized, Multicenter Trial Comparing Lactated Ringer’s Alone or With 5% Albumin for Resuscitation of Large Burns The Acute Burn ResUscitation Multicenter Prospective Trial 2 (ABRUPT2)

A three-part treatment combining antiretroviral therapy, broadly neutralizing antibodies and leronlimab permanently cleared HIV in newborn nonhuman primates when started within three days of infection, suggesting a potential path toward eliminating early-life HIV infections.

In more than 4,000 people, preexisting antibody patterns predicted responses to COVID-19 vaccination, with higher levels of antibodies to common microbes associated with stronger responses, suggesting past immune encounters may reveal a person’s baseline vaccine readiness.

Incidence of KRAS G12C mutations in genitourinary malignancies; emerging target in precision medicine

Survodutide Once Weekly for the Treatment of Adults with Obesity | New England Journal of Medicine

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