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Direct evidence for psychoactive cannabis use 2800 years ago

Earliest evidence of cannabis use found in ancient Siberian tomb

Disordered cannabis use increased risk of heart attack and stroke in a study of several million health records

Women with PMS-type symptoms smoked more cannabis in the days right before their period, and again around ovulation, a new study tracking daily use over 2–3 cycles found

The oldest securely dated direct proof that people used cannabis to get high comes from a 2,800-year-old royal tomb in Siberia, where scientists detected chemical traces of it in the hair of people buried there

A US study of over 1.3 million people with substance-related emergency care found 84% of adolescents aged 16–18 had at least one cannabis-related encounter, compared with 19% of adults aged 55–64

Cannabis legalisation and cardiovascular hospitalisations in the USA

Medical cannabis for the treatment of insomnia

Cannabis may not actually help you sleep better: a 35-year study of 1,266 U.S

Frequent cannabis use: association w seizure burden in drug-resistant epilepsy

Prenatal cannabis exposure was associated with alterations in large-scale functional brain network connectivity in late childhood, higher levels of psychopathology and significant differences across multiple cognitive domains, according to a study on 10,838 children (9-10 years)

Review of Studies on the Level of Cannabis Use and Risk of Psychosis

Medical Cannabis Dispensary Availability Improved Self-Reported Mental Health among Older Adults in New York

Cannabis linked to earlier onset of psychosis, with gap wider in older adults

Unexpected Findings Add New Insight on Cannabis and Heart Health—UCSF trial found fewer premature heartbeats after cannabis inhalation, with potential implications for atrial fibrillation risk.

Cannabis use predicts worse clinical outcomes in newly psychotic patients

One year after partial legalisation, there was no evidence of an immediate effect on the prevalence of cannabis use among young people in Germany

Cannabis users face substantially higher risk of heart attack (2025)

Effectiveness of Cannabis Sativa-Infused Drip Tea on Happiness Among Individuals Interested in Medical Cannabis-Based Care: A Quasi-Experimental Study

Scientists found a cannabis compound that relieves pain without the high

Removing criminal penalties for possessing cannabis for personal use, or introducing tightly controlled legalisation of cannabis, doesn’t appear to increase levels of cannabis use

Adolescent cannabis users have reduced ventral striatum activity during reward anticipation

Decline in IQ linked to frequent or dependent use of cannabis use in youth

Cannabis use during adolescence is associated with differences in brain regions involved in motivation and reward

Study: Patients With Hypermobility Disorders Experience Less Pain, Consume Fewer Opioids Following Medical Cannabis Treatment

Clinical Trial: Cannabis Oil Provides “Clinically Meaningful” Improvements in Fibromyalgia Symptoms

CDC: Four Percent of Adults Frequently Use Cannabis To Aid Sleep

Cannabis use does not reduce testosterone levels in young men and may even increase its testicular synthesis

The effect of collective trauma on craving for cannabis and tobacco

Cannabis and driving? Studies reveal big risks

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