FDA clears blood test to aid evaluation for Alzheimer's disease

Science investigation casts doubt on genes hailed as warding-off Alzheimer's disease

At least 1 in 4 former NFL players who died during 2016-21 had evidence of brain disease at death linked to repeated head impacts

While 93% of adults would take a new Alzheimer’s blood test, those closest to the disease might avoid it

Deep sleep brain waves offer protection against Alzheimer’s disease, new research shows

Learning Alzheimer’s disease signatures by bridging EEG with spiking neural networks and biophysical simulations

Birth order may influence your disease risk later in life

Common microplastic may increase risk of fatty liver disease

Berkeley Lab researchers make breakthrough in treatment of incurable Huntington’s disease

Research has found patients with inflammatory bowel disease (IBD) face a significantly higher risk of psychiatric disorders starting two to three years before diagnosis and lasting up to a decade after

Study finds that one in four former NFL players suffers from degenerative brain disease CTE

Glial-adjusted residual transcriptomics with leave-one-out transcriptome-wide association study influence analysis prioritizes GALNT6 and other high-impact genes in Alzheimer’s disease

Lymphatic vessels invade bone in disease but are absent in health and regeneration

Study of 376,511 people followed for up to 14 years found participation in colorectal cancer screening was associated with a 43% lower risk of dying from the disease, while being invited to screening was associated with a 26% lower risk.

Nobel Disease

GLP-1 drugs like Ozempic may help clear Alzheimer’s disease plaques, new systematic review suggests

Deep sleep brain waves during NREM offer protection against Alzheimer’s disease, suggesting that sleep quality may help counteract the cognitive risks associated with elevated levels of the neurotransmitter orexin

Among 28,720 People With Type 2 Diabetes, Women Were More Likely to Develop Mental Health Conditions, While Men More Often Developed Cardiovascular and Kidney Disease

Conceptual shift in TBI classification from the Glasgow Coma Scale to a new framework that integrates clinical and imaging features, biomarkers, and modifiers to improve disease characterization and describe disease trajectories

GLP-1 weight loss drugs such as Ozempic are linked with a lower risk of age‐related macular degeneration (AMD), a common eye disease that is the leading cause of irreversible vision loss in older adults.

The mRNA-LNP vaccine encoding viral VP2 confers effective protection against novel variant infectious bursal disease virus (nVarIBDV)

Show HN: 35k+ paper psychedelic library that knows LSD from Lumpy Skin Disease

Depression is linked to a smaller volume in a memory-related hippocampal region, according to brain scans of 2,009 cognitively healthy adults aged 50–90, independent of body mass index, physical activity, and several major biological indicators of Alzheimer's disease risk.

Researchers found a "genetic switch" that triggers neurodegeneration in both a rare childhood dementia and Alzheimer's disease due to waste build-up in microglia

Unexpected structure detected in the brains of humans and mice with Alzheimer’s disease - scientists pinpointed an entirely new pathological basis for the disease: an accumulation of mitochondrial plaques, due to the brain's inability to recycle its failing mitochondria.

A 38 year study of ~1 million adults (30 to 95 y) found lower red and processed meat intake was associated with a 1–5% lower risk of death from all causes, heart disease and cancer, while eating only white meat was linked to a 5–7% lower risk of all-cause mortality

Putting money where their mouth is: Anthropic’s Claude autonomously designs disease-targeting proteins with real wet-lab proof, hitting a 35% success rate vs 10–15% human average

Newborns immunized against RSV also had a 36% lower risk of invasive pneumococcal disease.

Risk of Parkinson’s disease may increase with prolonged exposure to road traffic noise

Bryan Johnson, the millionaire biohacker who wants to live forever, diagnosed with incurable autoimmune disease

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